Integrin beta 3 antibody [N2C1], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||87 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HUVEC , HUVEC treat with Sphingosine 1-phosphate|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)|
|Product Description||Rabbit Polyclonal antibody to Integrin beta 3 (integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61))|
|Background||The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq]|
|Synonyms||CD61 antibody, GP3A antibody, GPIIIa antibody, ITGB3 antibody, integrin beta-3 antibody, platelet glycoprotein IIIa antibody, platelet membrane glycoprotein IIIa antibody, "integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Integrin beta 3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rabbit, Chicken, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (95%), Dog (98%), Pig (96%), Rabbit (95%), Chicken (92%), Bovine (98%)|