Islet 1 antibody
|Applications||ICC/IF, IHC-Fr, IHC-P, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||39 kDa (note)
|Positive Controls||K562 whole cell extract , K562 nuclear extract , jurkat whole cell extract , jurkat nuclear extract , PC-12|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||ISL LIM homeobox 1|
|Product Description||Rabbit Polyclonal antibody to Islet 1 (ISL LIM homeobox 1)|
|Background||This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq]|
|Synonyms||ISLET1 antibody, Isl-1 antibody, ISL1 antibody, insulin gene enhancer protein ISL-1 antibody, "ISL1 transcription factor, LIM/homeodomain antibody", islet-1 antibody, ISL LIM homeobox 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Islet 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Japanese Medaka, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Zebrafish (97%), Japanese Medaka (97%), Xenopus laevis (96%), Chicken (99%), Bovine (100%)|