|Full Name||COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)|
|Product Description||Rabbit Polyclonal antibody to JAB1 (COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis))|
|Background||The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq]|
|Synonyms||CSN5 antibody, JAB1 antibody, MGC3149 antibody, MOV-34 antibody, SGN5 antibody, COPS5 antibody, jun activation domain-binding protein 1 antibody, signalosome subunit 5 antibody, 38 kDa Mov34 homolog antibody, COP9 signalosome complex subunit 5 antibody, COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human JAB1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (99%), Xenopus laevis (99%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)|