|Full Name||mitogen-activated protein kinase 9|
|Product Description||Rabbit Polyclonal antibody to JNK2 (mitogen-activated protein kinase 9)|
|Background||The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, p54a antibody, p54aSAPK antibody, MAPK9 antibody, stress-activated protein kinase 1a antibody, MAP kinase 9 antibody, stress-activated protein kinase JNK2 antibody, Jun kinase antibody, MAPK 9 antibody, c-Jun N-terminal kinase 2 antibody, c-Jun kinase 2 antibody, mitogen-activated protein kinase 9 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human JNK2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Chicken (89%)|