| Full Name | cadherin 6, type 2, K-cadherin (fetal kidney) |
| Background | This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq] |
| Synonyms | KCAD antibody, CDH6 antibody, cadherin-6 antibody, "cadherin 6, type 2, K-cadherin (fetal kidney) antibody" |
| Cellular Localization | Cell membrane |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human K-cadherin. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Chicken, Bovine |
| Predict Reactivity Note | Mouse (97%), Rat (96%), Chicken (82%), Bovine (97%) |
| Conjugation | Unconjugated |