|Full Name||solute carrier family 12 (potassium/chloride transporters), member 7|
|Product Description||Rabbit polyclonal antibody to KCC4 (solute carrier family 12 (potassium/chloride transporters), member 7)|
|Background||Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.|
|Synonyms||DKFZp434F076 antibody, KCC4 antibody, SLC12A7 antibody, potassium/chloride transporter KCC4 antibody, electroneutral potassium-chloride cotransporter 4 antibody, K-Cl cotransporter 4 antibody, solute carrier family 12 member 7 antibody, "solute carrier family 12 (potassium/chloride transporters), member 7 antibody"|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human KCC4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rabbit, Chicken|
|Predict Reactivity Note||Mouse (92%), Rat (91%), Rabbit (86%), Chicken (81%)|