|Full Name||lysine (K)-specific demethylase 4D|
|Product Description||Rabbit Polyclonal antibody to KDM4D (lysine-specific demethylase 4D)|
|Background||Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. |
|Synonyms||FLJ10251 antibody, JMJD2D antibody, MGC141909 antibody, KDM4D antibody, jumonji domain containing 2D antibody, jmjC domain-containing histone demethylation protein 3D antibody, jumonji domain-containing protein 2D antibody, lysine-specific demethylase 4D antibody, lysine (K)-specific demethylase 4D antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human KDM4D. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (88%), Rat (86%)|