|Product Description||Rabbit Polyclonal antibody to KIAA0196 (KIAA0196)|
|Background||This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases. [provided by RefSeq]|
|Synonyms||MGC111053 antibody, SPG8 antibody, KIAA0196 antibody, strumpellin antibody, WASH complex subunit strumpellin antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human KIAA0196. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Xenopus tropicalis (87%)|