KIDINS220 antibody [C3], C-term

Name: KIDINS220 antibody [C3], C-term
Brand: GeneTex
SKU: GTX110503
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-KIDINS220 antibody [C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX110503

Anti-KIDINS220 antibody [C3], C-term used in Western Blot (WB). GTX110503

Cat. No. GTX110503

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse
Package	100 μl ($399), 25 μl ($169)

See all KIDINS220 products

Datasheet
Document

View product citations for antibody GTX110503 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
IHC-P	1:100-1:1000

Not tested in other applications.

Calculated MW

197 kDa. ( Note )

Positive Control

H1299 , Raji

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human KIDINS220. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1950619

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kinase D interacting substrate 220 , ARMS , SINO

Cellular Localization

Membrane; Multi-pass membrane protein

Background

Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Database

Gene ID: 57498 KIDINS220
UniProt: Q9ULH0 KIDINS220

Research Area

DATA IMAGES

GTX110503 IHC-P Image

KIDINS220 antibody [C3], C-term detects KIDINS220 protein at membrane on mouse esophagus by immunohistochemical analysis.
Sample: Paraffin-embedded mouse esophagus.
KIDINS220 antibody [C3], C-term (GTX110503) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX110503 WB Image

Sample(30 ug whole cell lysate)
A:H1299
B:Raji (GTX27908)
5% SDS PAGE
GTX110503 diluted at 1:1000

GTX110503 IHC-P Image

Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using KIDINS220(GTX110503) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

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REVIEW