|Full Name||klotho beta|
|Product Description||Rabbit Polyclonal antibody to KLB (klotho beta)|
|Background||Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.|
|Synonyms||BKL antibody, MGC142213 antibody, KLB antibody, beta-klotho antibody, klotho beta-like protein antibody, betaKlotho antibody, klotho beta like antibody, klotho beta antibody|
|Cellular Localization||Cell membrane; Single-pass type III membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human KLB. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Bovine (91%)|