|Applications||FACS, IP, WB|
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||55 kDa (note)
|Positive Controls||A549 , HeLa , HepG2 , HCT116 , NIH-3T3 , human ESC , mouse ESC , HCT116 , HCT116 nuclear extract , Rat2 , *MDM-MB-231|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||Kruppel-like factor 4 (gut)|
|Product Description||Rabbit Polyclonal antibody to KLF4 (Kruppel-like factor 4 (gut))|
|Background||Transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. |
|Synonyms||EZF antibody, GKLF antibody, KLF4 antibody, endothelial Kruppel-like zinc finger protein antibody, Krueppel-like factor 4 antibody, gut-enriched krueppel-like factor antibody, epithelial zinc finger protein EZF antibody, Kruppel-like factor 4 (gut) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human KLF4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Cat, Pig, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Zebrafish (94%), Xenopus laevis (86%), Cat (100%), Pig (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%)|