|Full Name||kelch-like 21 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to KLHL21 (kelch-like 21 (Drosophila))|
|Background||Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. |
|Synonyms||KIAA0469 antibody, MGC99635 antibody, KLHL21 antibody, kelch-like protein 21 antibody, kelch-like 21 (Drosophila) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human KLHL21. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (95%), Rat (94%), Xenopus laevis (80%), Bovine (96%)|