|Full Name||killer cell lectin-like receptor subfamily C, member 1|
|Product Description||Rabbit Polyclonal antibody to NKG2A (killer cell lectin-like receptor subfamily C, member 1)|
|Background||Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]|
|Synonyms||CD159A antibody, MGC13374 antibody, MGC59791 antibody, NKG2 antibody, NKG2A antibody, KLRC1 antibody, NKG2-A/B-activating NK receptor antibody, NKG2-A/B type II integral membrane protein antibody, C-lectin type II protein antibody, CD159 antigen-like family member A antibody, NKG2-A/NKG2-B type II integral membrane protein antibody, natural killer cell lectin antibody, natural killer group protein 2 antibody, NKG2-1/B activating NK receptor antibody, NK cell receptor A antibody, "killer cell lectin-like receptor subfamily C, member 1 antibody"|
|Cellular Localization||Membrane; Single-pass type II membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NKG2A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|