|Full Name||killer cell lectin-like receptor subfamily C, member 4|
|Product Description||Rabbit polyclonal antibody to KLRC4 (killer cell lectin-like receptor subfamily C, member 4)|
|Background||Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript. [provided by RefSeq]|
|Synonyms||FLJ17759 antibody, FLJ78582 antibody, NKG2-F antibody, NKG2F antibody, KLRC4 antibody, NKG2-F-activating NK receptor antibody, NK cell receptor F antibody, natual killer cell group 2-F antibody, NKG2-F type II integral membrane protein antibody, "killer cell lectin-like receptor subfamily C, member 4 antibody"|
|Cellular Localization||Membrane; Single-pass type II membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|