KPNA4 antibody [C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||58 kDa (note)
|Positive Controls||293T , HeLa , HepG2 , Molt-4 , Raji , *A549 |
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||karyopherin alpha 4 (importin alpha 3)|
|Product Description||Rabbit Polyclonal antibody to KPNA4 (karyopherin alpha 4 (importin alpha 3))|
|Background||The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq]|
|Synonyms||IPOA3 antibody, MGC12217 antibody, MGC26703 antibody, QIP1 antibody, SRP3 antibody, KPNA4 antibody, importin alpha Q1 antibody, importin subunit alpha-4 antibody, karyopherin subunit alpha-4 antibody, karyopherin alpha 4 (importin alpha 3) antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KPNA4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%), Bovine (100%)|