|Full Name||kallikrein-related peptidase 6|
|Product Description||Rabbit Polyclonal antibody to Kallikrein 6 (kallikrein-related peptidase 6)|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]|
|Synonyms||Bssp antibody, Klk7 antibody, MGC9355 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, KLK6 antibody, serine protease 9 antibody, kallikrein-6 antibody, neurosin antibody, protease M antibody, serine protease 18 antibody, zyme antibody, kallikrein-related peptidase 6 antibody|
|Cellular Localization||Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Dog (88%), Rhesus Monkey (98%), Bovine (83%)|