Kinectin 1A antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||156 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||kinectin 1 (kinesin receptor)|
|Product Description||Rabbit Polyclonal antibody to Kinectin 1A (kinectin 1 (kinesin receptor))|
|Background||Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]|
|Synonyms||CG1 antibody, KIAA0004 antibody, KNT antibody, MGC133337 antibody, MU-RMS-40.19 antibody, KTN1 antibody, CG-1 antigen antibody, kinesin receptor antibody, kinectin antibody, kinectin 1 (kinesin receptor) antibody|
|Cellular Localization||Endoplasmic reticulum membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Kinectin 1A. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Pig (93%)|