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Kv1.3 antibody

Anti-Kv1.3 antibody used in Western Blot (WB). GTX16679
Anti-Kv1.3 antibody used in Live cell imaging (LCI). GTX16679
Anti-Kv1.3 antibody used in Western Blot (WB). GTX16679
Anti-Kv1.3 antibody used in Flow cytometry (FACS). GTX16679

Cat. No. GTX16679

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, FACS, IP, IHC, LCI

Reactivity

Human, Mouse, Rat
Package
50 μl ($639)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
IHC Assay dependent
LCI Assay dependent
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide KDYPASTSQDSFEA(C), corresponding to amino acid residues 263-276 (Extracellular loop between domains S1 and S2) of human KV1.3 (Accession P22001).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily A member 3 , HGK5 , HLK3 , HPCN3 , HUKIII , KV1.3 , MK3 , PCN3

Cellular Localization

Cell membrane

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Kv1.3 antibody used in Western Blot (WB). GTX16679

GTX16679 WB Image

WB analysis of Jurkat cell lysates using GTX16679 Kv1.3 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-Kv1.3 antibody used in Live cell imaging (LCI). GTX16679

GTX16679 LCI Image

Live cell imaging analysis of live intact HEK 293 cells transfected with rat KV1.3 (panels A and C) or with empty vector (panels B and D) using GTX16679 Kv1.3 antibody.
Green : Primary antibody
Dilution : 1:50

Anti-Kv1.3 antibody used in Western Blot (WB). GTX16679

GTX16679 WB Image

WB analysis of rat brain membrane lysate using GTX16679 Kv1.3 antibody preincubated with or without immunogen peptide.
Dilution : 1:500

Anti-Kv1.3 antibody used in Flow cytometry (FACS). GTX16679

GTX16679 FACS Image

FACS analysis of Jurkat cells using GTX16679 Kv1.3 antibody.
Black : Unstained cell
Green : Cell staining with primary antibody
Dilution : 1:25

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639