|Full Name||potassium voltage-gated channel, Shal-related subfamily, member 2|
|Product Description||Rabbit Polyclonal antibody to Kv4.2 (potassium voltage-gated channel, Shal-related subfamily, member 2)|
|Background||Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels. [provided by RefSeq]|
|Synonyms||KIAA1044 antibody, KV4.2 antibody, MGC119702 antibody, MGC119703 antibody, RK5 antibody, KCND2 antibody, voltage-sensitive potassium channel antibody, voltage-gated potassium channel subunit Kv4.2 antibody, potassium voltage-gated channel subfamily D member 2 antibody, voltage-gated potassium channel Kv4.2 antibody, "potassium voltage-gated channel, Shal-related subfamily, member 2 antibody"|
|Cellular Localization||Cell membrane; Multi-pass membrane protein , Cell projection , dendrite |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Kv4.2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Rabbit, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (81%), Rabbit (98%), Chicken (90%), Rhesus Monkey (99%), Bovine (98%)|