| Catalog Number | GTX103214 |
| Product Name | LAMP2 antibody
see all 'LAMP2' products |
| Full Name | lysosomal-associated membrane protein 2 |
| Synonyms | CD107b antibody | LAMPB antibody | LGP110 antibody | LAMP2 antibody | CD107 antigen-like family member B antibody | lysosome-associated membrane glycoprotein 2 antibody | lysosome-associated membrane protein 2 antibody | lysosomal-associated membrane protein 2 antibody |
| Product Description | Rabbit Polyclonal antibody to LAMP2 (lysosomal-associated membrane protein 2) |
| Background | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq] |
| Host | Rabbit |
| Clonality | Polyclonal |
| Subclass | IgG |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 20 and 267 of LAMP2 (Uniprot ID#P13473) |
| Antigen Species | Human |
| Species Reactivity | Human |
| Applications | ICC/IF, IHC (Formalin-fixed paraffin-embedded sections), Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Positive Controls | A549 | HeLa | HepG2 | HCT116 | *F79 | *F123 | |
| Predicted Target Size(KDa) | 45 (Note) |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein | Endosome membrane; Single-pass type I membrane protein | Lysosome membrane; Single-pass type I membrane protein | |
| Form Supplied | Liquid |
| Concentration | 1 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |