Full Name | microtubule-associated protein 1 light chain 3 alpha |
Background | MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012] |
Synonyms | MAP1BLC3 Antibody , MAP1ALC3 Antibody , ATG8E Antibody , microtubule-associated protein 1 light chain 3 alpha Antibody , MAP1LC3A Antibody , LC3 Antibody |
Specificity | Multiple isoforms are known to exist. This antibody is predicted to detect LC3A, LC3B, and LC3C. |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | LC3A antibody was raised against a 12 amino acid peptide near the center of human LC3AA.The immunogen is located within amino acids 20 - 70 of LC3A. |
Antigen Species | Human |
Species Reactivity | Human, Mouse, Rat |
Conjugation | Unconjugated |