|Full Name||LIM domain binding 2|
|Product Description||Rabbit Polyclonal antibody to LDB2 (LIM domain binding 2)|
|Background||Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins (summarized by Semina et al., 1998 [PubMed 9799849]). These proteins, such as the one encoded by the LDB2 gene, are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes (Jurata and Gill, 1997 [PubMed 9315627]). The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse, Clim1 (Bach et al., 1997 [PubMed 9192866]) and Clim2/Lbd1/Nli (Agulnick et al., 1996 [PubMed 8918878]; Jurata et al., 1996 [PubMed 8876198]; Bach et al., 1997 [PubMed 9192866]) and their homologs cloned from the frog, chicken, and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.[supplied by OMIM]|
|Synonyms||CLIM1 antibody, LDB1 antibody, LDB2 antibody, LIM domain-binding factor-2 antibody, LDB-2 antibody, LIM domain-binding factor CLIM1 antibody, carboxyl-terminal LIM domain-binding protein 1 antibody, CLIM-1 antibody, LIM binding domain 2 antibody, LIM domain-binding protein 2 antibody, LIM domain binding 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LDB2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (96%), Chicken (95%), Rhesus Monkey (100%), Bovine (98%)|