|Full Name||lymphoid enhancer-binding factor 1|
|Product Description||Rabbit Polyclonal antibody to LEF1 (lymphoid enhancer-binding factor 1)|
|Background||LEF1 is a nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905) (Waterman et al., 1991 [PubMed 2010090]; van Genderen et al., 1994 [PubMed 7958926]).[supplied by OMIM]|
|Synonyms||LEF-1 Antibody , lymphoid enhancer-binding factor 1 Antibody , TCF10 Antibody , TCF7L3 Antibody , TCF1ALPHA Antibody|
|Cellular Localization||Nucleus (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human LEF1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Pig (96%), Bovine (98%)|