|Full Name||leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2|
|Product Description||Rabbit polyclonal antibody to LILRA2 (leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2)|
|Background||Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM]|
|Synonyms||CD85H antibody, ILT1 antibody, LIR-7 antibody, LIR7 antibody, LILRA2 antibody, leukocyte immunoglobulin-like receptor subfamily A member 2 antibody, leukocyte immunoglobulin-like receptor subfamily A member 2 soluble antibody, leukocyte immunoglobulin-like receptor 7 antibody, CD85 antigen-like family member H antibody, immunoglobulin-like transcript 1 antibody, ILT-1 antibody, "leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LILRA2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (85%), Chimpanzee (95%)|