|Full Name||leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3|
|Product Description||Rabbit Polyclonal antibody to LILRA3 (leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3)|
|Background||Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM]|
|Synonyms||CD85E antibody, HM31 antibody, HM43 antibody, ILT6 antibody, LIR-4 antibody, LIR4 antibody, e3 antibody, LILRA3 antibody, leukocyte immunoglobulin-like receptor subfamily A member 3 antibody, monocyte inhibitory receptor HM43/HM31 antibody, leucocyte immunoglobulin-like receptor antibody, leukocyte immunoglobulin-like receptor 4 antibody, leukocyte immunoglobulin-like receptor A3 antibody, immunoglobulin-like transcript 6 antibody, CD85 antigen-like family member E antibody, ILT-6 antibody, "leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LILRA3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (91%), Chimpanzee (91%)|