|Full Name||leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5|
|Product Description||Rabbit polyclonal antibody to LILRB5 (leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5)|
|Background||This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CD85C antibody, LIR-8 antibody, LIR8 antibody, LILRB5 antibody, leukocyte immunoglobulin-like receptor 8 antibody, CD85 antigen-like family member C antibody, leukocyte immunoglobulin-like receptor subfamily B member 5 antibody, "leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 antibody"|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LILRB5. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (94%)|