LIMS1 antibody [C2C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||37 kDa (note)
|Positive Controls||Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||LIM and senescent cell antigen-like domains 1|
|Product Description||Rabbit polyclonal antibody to LIMS1 (LIM and senescent cell antigen-like domains 1)|
|Background||The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]|
|Synonyms||PINCH antibody, PINCH1 antibody, LIMS1 antibody, renal carcinoma antigen NY-REN-48 antibody, particularly interesting new Cys-His protein 1 antibody, LIM and senescent cell antigen-like-containing domain protein 1 antibody, LIM and senescent cell antigen-like domains 1 antibody|
|Cellular Localization||Cell junction , focal adhesion , Cell membrane; Peripheral membrane protein; Cytoplasmic side |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LIMS1. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Zebrafish, Xenopus laevis, Pig, Chicken|
|Predict Reactivity Note||Human (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%)|