|Full Name||serine/threonine kinase 10|
|Product Description||Rabbit Polyclonal antibody to LOK (serine/threonine kinase 10)|
|Background||This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq]|
|Synonyms||LOK antibody, PRO2729 antibody, STK10 antibody, lymphocyte-oriented kinase antibody, serine/threonine-protein kinase 10 antibody, serine/threonine kinase 10 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human LOK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Zebrafish (82%), Xenopus laevis (84%), Chicken (90%), Bovine (96%)|