|Full Name||lon peptidase 1, mitochondrial|
|Product Description||Rabbit Polyclonal antibody to LONP1|
|Background||This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]|
|Synonyms||LonHS Antibody, hLON Antibody, LONP Antibody, PRSS15 Antibody, PIM1 Antibody, LON Antibody, lon peptidase 1, mitochondrial Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from human LONP1 (375-420aa)|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Horse, Pig, Chicken, Dog|