|Full Name||lysyl oxidase-like 1|
|Product Description||Rabbit Polyclonal antibody to LOXL1 (lysyl oxidase-like 1)|
|Background||This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]|
|Synonyms||LOL antibody, LOXL antibody, LOXL1 antibody, lysyl oxidase-like protein 1 antibody, lysyl oxidase homolog 1 antibody, lysyl oxidase-like 1 antibody|
|Cellular Localization||Secreted , extracellular space |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LOXL1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (97%), Zebrafish (87%), Xenopus laevis (91%), Bovine (99%)|