|Full Name||lysyl oxidase-like 4|
|Product Description||Rabbit Polyclonal antibody to LOXL4 (lysyl oxidase-like 4)|
|Background||This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]|
|Synonyms||FLJ21889 antibody, LOXC antibody, LOXL4 antibody, lysyl oxidase related C antibody, lysyl oxidase homolog 4 antibody, lysyl oxidase-like protein 4 antibody, lysyl oxidase-related protein C antibody, lysyl oxidase-like 4 antibody|
|Cellular Localization||Secreted , extracellular space |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human LOXL4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (92%), Rat (91%), Bovine (90%)|