|Full Name||low density lipoprotein receptor-related protein 1|
|Product Description||Rabbit Polyclonal antibody to LRP1 (85kDa subunit) (low density lipoprotein receptor-related protein 1)|
|Background||The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq]|
|Synonyms||LRP1A Antibody , A2MR Antibody , LRP Antibody , TGFBR5 Antibody , CD91 Antibody , APR Antibody , APOER Antibody , IGFBP3R Antibody , low density lipoprotein receptor-related protein 1 Antibody , LRP1 Antibody|
|Cellular Localization||Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein , Membrane , coated pit , Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein;|
|Target||LRP1 (85kDa subunit)|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human LRP1 (85kDa subunit). The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Chicken (96%)|