LRP1 antibody [A2Mr alpha-2]
|Applications||ELISA, FACS, ICC/IF, IHC-Fr, IP, WB|
| ELISA||Assay-dependent dilution
| Immunocytochemistry/ Immunofluorescence||Assay-dependent dilution
| IHC (Frozen sections)||Assay-dependent dilution
| Immunoprecipitation||Assay-dependent dilution
| Western blot||Assay-dependent dilution
Flow cytometry/FACS : Use 10μl of the suggested working dilution to label 106 cells in 100μl.Not tested in other applications.
Western blot : This antibody recognizes LRP1 under non-reducing conditions.
*Optimal dilutions/concentrations should be determined by the researcher.
(Please refer to the vial label for the specific concentration)|
|Purification||Protein G purified|
|Purification Note||From tissue culture supernatant|
|Full Name||LDL receptor related protein 1|
|Product Description||Mouse monoclonal antibody [A2Mr alpha-2] to LRP1|
|Background||The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. [provided by RefSeq, Jan 2010]|
|Synonyms||LRP1A Antibody , A2MR Antibody , LRP Antibody , TGFBR5 Antibody , CD91 Antibody , APR Antibody , IGFBP3R Antibody , APOER Antibody|
|Specificity||This antibody detects an epitope within the LRP515 chain of LRP1 (CD91).|
|Clone Name||A2Mr alpha-2|