|Full Name||leucine-rich repeat kinase 2|
|Product Description||Rabbit Polyclonal antibody to LRRK2 (leucine-rich repeat kinase 2)|
|Background||This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq]|
|Synonyms||AURA17 antibody, DARDARIN antibody, PARK8 antibody, RIPK7 antibody, ROCO2 antibody, LRRK2 antibody, leucine-rich repeat serine/threonine-protein kinase 2 antibody, augmented in rheumatoid arthritis 17 antibody, leucine-rich repeat kinase 2 antibody|
|Cellular Localization||Cytoplasm , Membrane; Peripheral membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human LRRK2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Bovine|
|Predict Reactivity Note||Rat (83%), Pig (87%), Bovine (89%)|