LYAG antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||105 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||glucosidase, alpha; acid|
|Product Description||Rabbit polyclonal antibody to LYAG (glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II))|
|Background||This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||LYAG antibody, GAA antibody, lysosomal alpha-glucosidase antibody, aglucosidase alfa antibody, acid maltase antibody, "glucosidase, alpha, acid antibody"|
|Cellular Localization||Lysosome |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human LYAG. The exact sequence is proprietary.|