| Full Name | lamin B1 |
| Product Description | Rabbit Polyclonal antibody to Lamin B1 (lamin B1) |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq] |
| Synonyms | ADLD antibody, LMN antibody, LMN2 antibody, LMNB antibody, MGC111419 antibody, LMNB1 antibody, lamin-B1 antibody, lamin B1 antibody |
| Cellular Localization | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Lamin B1. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Chicken, Rhesus Monkey, Chimpanzee, Bovine |
| Predict Reactivity Note | Mouse (98%), Rat (98%), Chicken (91%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (99%) |
| Conjugation | Unconjugated |