| Full Name | latrophilin 1 |
| Product Description | Rabbit Polyclonal antibody to Latrophilin-1 |
| Background | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] |
| Synonyms | LPHN1 Antibody , CL1 Antibody , CIRL1 Antibody , LEC2 Antibody , latrophilin 1 Antibody |
| Specificity | Recognizes endogenous levels of LPHN1 protein. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | Latrophilin-1 |
| Isotype | IgG |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LPHN1. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |