|Full Name||leucine rich repeat and Ig domain containing 1|
|Product Description||Rabbit Polyclonal antibody to Lingo-1 (leucine rich repeat and Ig domain containing 1)|
|Background||Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.|
|Synonyms||FLJ14594 antibody, LERN1 antibody, LRRN6A antibody, MGC17422 antibody, UNQ201 antibody, LINGO1 antibody, leucine rich repeat neuronal 6A antibody, leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 antibody, leucine-rich repeat neuronal protein 1 antibody, leucine-rich repeat and immunoglobilin domain-containing protein 1 antibody, leucine-rich repeat neuronal protein 6A antibody, leucine rich repeat and Ig domain containing 1 antibody|
|Cellular Localization||Cell membrane; Single-pass type I membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Lingo-1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Chicken (92%)|