|Full Name||metastasis associated in colon cancer 1|
|Product Description||Rabbit Polyclonal antibody to MACC1 (metastasis associated in colon cancer 1)|
|Background||MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]|
|Synonyms||7A5 antibody , MACC1 antibody , MACC1 antibody , SH3 domain-containing protein 7a5 antibody , SH3BP4L antibody , metastasis associated in colon cancer 1 antibody , metastasis-associated in colon cancer protein 1 antibody , putative binding protein 7a5 antibody|
|Cellular Localization||Cytoplasm , Nucleus|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (80%)|