|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||18 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , mouse muscle , rat muscle|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)|
|Product Description||Rabbit Polyclonal antibody to MAFG (v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian))|
|Background||Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM]|
|Synonyms||MGC13090 antibody, MGC20149 antibody, MAFG antibody, transcription factor MafG antibody, basic leucine zipper transcription factor MafG antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MAFG. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Chicken (92%), Rhesus Monkey (100%), Bovine (98%)|