|Full Name||v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)|
|Product Description||Rabbit Polyclonal antibody to MAFK (v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian))|
|Background||The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM]|
|Synonyms||v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) Antibody, P18 Antibody, NFE2U Antibody|
|Immunogen||Full length human MAFK Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Chicken, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (97%), Zebrafish (83%), Chicken (93%), Bovine (92%)|