|Full Name||membrane associated guanylate kinase, WW and PDZ domain containing 3|
|Product Description||Rabbit Polyclonal antibody to MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3)|
|Background||Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.|
|Synonyms||MAGI-3 antibody, MGC163281 antibody, RP4-730K3.1 antibody, dJ730K3.2 antibody, MAGI3 antibody, membrane-associated guanylate kinase inverted 3 antibody, "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 antibody", membrane-associated guanylate kinase-related 3 antibody, "membrane associated guanylate kinase, WW and PDZ domain containing 3 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human MAGI3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (95%), Chicken (93%), Bovine (96%)|