|Full Name||methylcrotonoyl-CoA carboxylase 1 (alpha)|
|Product Description||Rabbit polyclonal antibody to MCCA (methylcrotonoyl-Coenzyme A carboxylase 1 (alpha))|
|Background||This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq]|
|Synonyms||DKFZp686B20267 antibody, FLJ25545 antibody, MCC-B antibody, MCCA antibody, MCCC1 antibody, "methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial antibody", 3-methylcrotonyl-CoA carboxylase 1 antibody, methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) antibody, 3-methylcrotonyl-CoA carboxylase biotin-containing subunit antibody, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha antibody, MCCase subunit alpha antibody, methylcrotonoyl-CoA carboxylase 1 (alpha) antibody|
|Cellular Localization||Mitochondrion matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MCCA. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Chicken, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (92%), Rat (92%), Zebrafish (84%), Chicken (88%), Bovine (95%)|