MCD antibody [N2C1], Internal
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||55 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , C8D30|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||malonyl-CoA decarboxylase|
|Product Description||Rabbit Polyclonal antibody to MCD (malonyl-CoA decarboxylase)|
|Background||The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq]|
|Synonyms||MCD antibody, MGC59795 antibody, MLYCD antibody, malonyl coenzyme A decarboxylase antibody, "malonyl-CoA decarboxylase, mitochondrial antibody", malonyl-CoA decarboxylase antibody|
|Cellular Localization||Mitochondrion , Cytoplasm , Peroxisome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MCD. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (93%), Bovine (89%)|