|Full Name||myeloid cell leukemia sequence 1 (BCL2-related)|
|Product Description||Rabbit Polyclonal antibody to MCL1 (myeloid cell leukemia sequence 1 (BCL2-related))|
|Background||The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq]|
|Synonyms||BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, MGC104264 antibody, MGC1839 antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, MCL1 antibody, myeloid cell leukemia ES antibody, bcl-2-like protein 3 antibody, bcl-2-related protein EAT/mcl1 antibody, induced myeloid leukemia cell differentiation protein Mcl-1 antibody, myeloid cell leukemia sequence 1 (BCL2-related) antibody|
|Cellular Localization||Membrane; Single-pass membrane protein (Potential) , Cytoplasm , Mitochondrion , Nucleus , nucleoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MCL1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Cat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (88%), Dog (91%), Cat (91%), Rhesus Monkey (99%), Bovine (90%)|