|Full Name||Mdm4 p53 binding protein homolog (mouse)|
|Product Description||Rabbit Polyclonal antibody to MDMX (protein Mdm4)|
|Background||The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp781B1423 antibody, HDMX antibody, MDMX antibody, MGC132766 antibody, MRP1 antibody, MDM4 antibody, mdm2-like p53-binding protein antibody, protein Mdm4 antibody, "double minute 4, human homolog of, p53-binding protein antibody", protein Mdmx antibody, MDM4-related protein 1 antibody, "Mdm4, transformed 3T3 cell double minute 4, p53 binding protein antibody", Mdm4 p53 binding protein homolog (mouse) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MDMX. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (83%), Chimpanzee (99%), Bovine (84%)|