|Full Name||mediator complex subunit 17|
|Product Description||Rabbit Polyclonal antibody to MED17 (mediator complex subunit 17)|
|Background||The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq]|
|Synonyms||CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, FLJ10812 antibody, TRAP80 antibody, MED17 antibody, vitamin D3 receptor-interacting protein complex 80 kDa component antibody, ARC77 antibody, activator-recruited cofactor 77 kDa component antibody, mediator of RNA polymerase II transcription subunit 17 antibody, "cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa antibody", CRSP complex subunit 6 antibody, thyroid hormone receptor-associated protein complex 80 kDa component antibody, transcriptional coactivator CRSP77 antibody, mediator complex subunit 17 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human MED17. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (98%), Zebrafish (85%), Chicken (94%), Rhesus Monkey (100%), Bovine (96%)|