|Full Name||mediator complex subunit 27|
|Product Description||Rabbit Polyclonal antibody to MED27 (mediator complex subunit 27)|
|Background||The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq]|
|Synonyms||TRAP37 Antibody , CRAP34 Antibody , CRSP34 Antibody , mediator complex subunit 27 Antibody , CRSP8 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MED27. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (97%), Zebrafish (87%), Pig (97%), Chicken (88%), Rhesus Monkey (100%), Bovine (96%)|