|Full Name||mitogen-activated protein kinase kinase 1|
|Product Description||Rabbit polyclonal antibody to MEK1|
|Background||The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]|
|Synonyms||Phospho MEK1 (pSer218/222) Antibody , Phospho MEK1 (pS218/222) Antibody , MEK1 Ser218/222 phospho Antibody , MEK1 S218/222 phospho Antibody , phospho Ser218/222 MEK1 Antibody , PRKMK1 Antibody , MEK1 phospho Antibody , MKK1 Antibody , phospho S218/222 MEK1 Antibody , MEK1 phospho S218/222 Antibody , MAP2K1 Antibody , MEK1 phospho Ser218/222 Antibody , MEK1 (Phospho S218/222) Antibody , Phospho MEK1 (Ser218/222) Antibody , MEK1 (pSer218/222) Antibody , MEK1 (pS218/222) Antibody , phospho MEK1 S218/222 Antibody , phospho MEK1 Ser218/222 Antibody , MAPKK1 Antibody , MEK1 (Phospho Ser218/222) Antibody , phospho MEK1 Antibody|
|Specificity||This antibody is specific for MEK 1 and MEK 2 when phosphorylated at serine 218 and 222.|
|Target||Mek 1/2 (phospho Ser218/222)|
|Immunogen||Synthetic phosphopeptide corresponding to an amino acid sequence which includes phosphorylated ser 218 and 222 within human MEK1 and 2.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|zebrafish, Xenopus laevis, Rat, Monkey, Dog, Chicken, Bovine|