|Full Name||mitogen-activated protein kinase kinase 7|
|Product Description||Rabbit Polyclonal antibody to MEK7 (mitogen-activated protein kinase kinase 7)|
|Background||The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq]|
|Synonyms||Jnkk2 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, MAP2K7 antibody, MAPKK 7 antibody, c-Jun N-terminal kinase kinase 2 antibody, JNK-activating kinase 2 antibody, MEK 7 antibody, MAP kinase kinase 7 antibody, dual specificity mitogen-activated protein kinase kinase 7 antibody, MAPK/ERK kinase 7 antibody, JNKK 2 antibody, SAPK kinase 4 antibody, stress-activated protein kinase kinase 4 antibody, mitogen-activated protein kinase kinase 7 antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MEK7. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Sheep|
|Predict Reactivity Note||Mouse (99%), Rat (99%), Zebrafish (88%), Sheep (99%)|